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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BRSK1 All Species: 21.21
Human Site: Y123 Identified Species: 46.67
UniProt: Q8TDC3 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8TDC3 NP_115806.1 794 86753 Y123 Y E N K K Y L Y L V L E H V S
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_541413 801 87720 Y130 Y E N K K Y L Y L V L E H V S
Cat Felis silvestris
Mouse Mus musculus Q5RJI5 778 85136 Y107 Y E N K K Y L Y L V L E H V S
Rat Rattus norvegicus O08679 722 80853 M104 L F R E V R I M K V L N H P N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514667 306 34673
Chicken Gallus gallus Q9IA88 798 88848 Y99 M E T K D M L Y I V T E F A K
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q6NSM8 1187 130949 Y132 M E T E R M I Y L V T E Y A S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_648814 861 95238 D104 V S G G E L F D Y L V K K G R
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9TW45 1192 126331 Y243 M E T E Q T L Y L V L E Y A S
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q38997 535 61163
Baker's Yeast Sacchar. cerevisiae P34244 1518 169574 Y190 W E N K S E L Y L V L E Y V D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 98.1 N.A. 94.8 29.2 N.A. 32.1 28.3 N.A. 25.1 N.A. 48.5 N.A. 25.7 N.A.
Protein Similarity: 100 N.A. N.A. 98.2 N.A. 95.4 44.5 N.A. 33.3 43.9 N.A. 38.5 N.A. 62.5 N.A. 37.9 N.A.
P-Site Identity: 100 N.A. N.A. 100 N.A. 100 20 N.A. 0 40 N.A. 40 N.A. 0 N.A. 53.3 N.A.
P-Site Similarity: 100 N.A. N.A. 100 N.A. 100 40 N.A. 0 46.6 N.A. 66.6 N.A. 26.6 N.A. 73.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 27 22.2 N.A.
Protein Similarity: N.A. N.A. N.A. 41.9 34.2 N.A.
P-Site Identity: N.A. N.A. N.A. 0 66.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 0 80 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 28 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 10 0 0 10 0 0 0 0 0 0 10 % D
% Glu: 0 64 0 28 10 10 0 0 0 0 0 64 0 0 0 % E
% Phe: 0 10 0 0 0 0 10 0 0 0 0 0 10 0 0 % F
% Gly: 0 0 10 10 0 0 0 0 0 0 0 0 0 10 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 37 0 0 % H
% Ile: 0 0 0 0 0 0 19 0 10 0 0 0 0 0 0 % I
% Lys: 0 0 0 46 28 0 0 0 10 0 0 10 10 0 10 % K
% Leu: 10 0 0 0 0 10 55 0 55 10 55 0 0 0 0 % L
% Met: 28 0 0 0 0 19 0 10 0 0 0 0 0 0 0 % M
% Asn: 0 0 37 0 0 0 0 0 0 0 0 10 0 0 10 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % P
% Gln: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 10 0 10 10 0 0 0 0 0 0 0 0 10 % R
% Ser: 0 10 0 0 10 0 0 0 0 0 0 0 0 0 46 % S
% Thr: 0 0 28 0 0 10 0 0 0 0 19 0 0 0 0 % T
% Val: 10 0 0 0 10 0 0 0 0 73 10 0 0 37 0 % V
% Trp: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 28 0 0 0 0 28 0 64 10 0 0 0 28 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _